"Chapter I of this year’s World Drug Report provides an overview of recent trends and the drug situation in terms of production, trafficking and consumption and the consequences of illicit drug use in terms of treatment, drugrelated diseases and drug-related deaths. Chapter II presents a long-term perspective on the characteristics and evolution of the drug problem and the main factors that shaped it. It starts with a discussion of the main characteristics of the contemporary drug problem, followed by an overview of the shifts observed over the last few de cades, before concluding with an analysis of the driving factors that shaped the evolution of the drug problem, including a brief outlook for its likely future direction. CHAPTER I. RECENT STATISTICS AND TREND ANALYSIS OF ILLICIT DRUG MARKETS Latest available data indicate that there has been no significant change in the global status quo regarding the use, production and health consequences of illicit drugs, other than the return to high levels of opium production in Afghanistan after a disease of the opium poppy and subsequent crop failure in 2010. But while the troubled waters of the world’s illicit drug markets may appear to be stagnant, shifts and changes in their flows and currents can be observed below the surface. These are significant and also worrying, not because of how they currently impact on the data but because they are proof of the resilience and adaptability of illicit drug suppliers and users and because of the potential future repercussions of those shifts and changes in the world’s major drug markets. The global picture The extent of global illicit drug use remained stable in the five years up to and including 2010, at between 3.4 and 6.6 per cent of the adult population (persons aged 15-64). However, some 10-13 per cent of drug users continue to be problem users with drug dependence and/or drug-use disorders, the prevalence of HIV (estimated at approximately 20 per cent), hepatitis C (46.7 per cent) and hepatitis B (14.6 per cent) among injecting drug users continues to add to the global burden of disease, and, last but not least, approximately 1 in every 100 deaths among adults is attributed to illicit drug use. Opioids continue to be the dominant drug type accounting for treatment demand in Asia and Europe and also contribute considerably to treatment demand in Africa, North America and Oceania. Treatment for cocaine use is mainly associated with the Americas, while cannabis is the main drug causing treatment demand in Africa. Demand for treatment relating to the use of amphetamine-type stimulants (ATS) is most common in Asia..."